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 2002 Anniversary Issue Introduction
Model Portfolio review reveals tasty tidbits
In October 2001, we issued our first publication as Biotech Monthly. Building upon over two years of successful market prognostication at NymbleInvestor.com, our Research Team decided to dedicate themselves to perhaps the most fascinating sector in the market.

We've had some successes since our first issue. We've been the only firm to correctly call the Provenge situation at Dendreon (DNDN). We've made good calls with PAREXEL (PRXL) and Indevus (IDEV). We’re obviously on the right track with ID Biomedical (IDBE). We even feel relatively happy about our efforts on Genta (GNTA).

The overall picture isn't as good. As of this writing, we're down nearly 30% in the NIBM Model Portfolio since inception. Although we consistently beat the AMEX Biotech Index and the NASDAQ during the same period, we're not exactly content. At NymbleInvestor.com, we beat the S&P-500 by 60 points and the NASDAQ by 80. We're not used to seeing our performance numbers in the red.

Click here for information on purchasing the Anniversary Issue

The good news is we're making progress. The macro market will begin to go our way now that October is behind us. As you'll read in the next few dozen pages, a significant number of the companies in our Model Portfolio have verification of the efficacy of their drug candidates. The publication/meeting schedule for our companies over the next two months and at the ASCO meeting in June is exceptionally heavy - largely featuring abstracts on positive clinical trials.

In short, Q4-2002 and 2003 should be good, perhaps exceptional, for our Model Portfolio.

About the format
We were able to conduct interviews with management from every company in our Model Portfolio but Titan Pharmaceutical (AMEX:TTP), who refused, and Nabi (NABI), who never responded. These interviews were illuminating in nearly every case and we believe you'll find the subsequent updates worthwhile.

The companies are in a specific order. Our Model Portfolio is predicated on the idea the only safe investment in development-stage biotechnology companies is a balanced and well-diversified one. Without limiting the importance of that point, we also realize most of our Subscribers will need to pick and choose among companies in order to begin the diversification process.

We've organized the issue with this process in mind. We've placed the companies in order from most- to least promising. We've chosen ID Biomedical to lead the pack, for reasons that will become obvious when you read the story. Truth be told, it would be hard to go wrong by starting your diversification program with any of the top three companies in this issue.

In addition to company-specific queries, the NIBM Research Team asked each management team the same set of five questions. We'll share the answers to those questions in each section. In a couple of weeks, we'll share with Subscribers our commentary on these answers - sort of a post-game summary of the interesting things we heard from management teams around the country.

Three interviews into this process we realized the volume of information we were receiving was more than we expected. Our original idea of providing two-three pages of technology summary for each company quickly went out the window. We'll certainly speak about technology and science, but expect to see many instances where we refer you to a previous NIBM Newsletter for specific details. All are available to Subscribers on the Biotech Monthly web site. For our single-issue purchasers, perhaps you will consider joining our family of Subscribers so you can access those publications.

One priority in each conversation was to obtain updated development timelines for each company. We also tried to focus on timing for near-term events such as presentations at scientific conferences. We'll have a table and a discussion of the timelines in each of the segments.

Because this issue is so lengthy, we've eliminated the Recommended Readings section. Biotech Monthly President David Miller's Macro Market Commentary column has been included, however.

We hope you'll enjoy this issue. While it is a review, there is enough new information in here to be worthwhile. We're making a few important changes to our Model Portfolio along the way, so pay attention for those.

As always, we're happy to receive any questions and/or comments. Just send us an e-mail.

For a table of contents, click here.
 
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