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 January 2002 (v02-n01)
Main Story - pgs. 1-23 Sector Survey: Contract Research Organizations
Macro Market Commentary - pg. 24-25
News Briefs - pgs. 26-27
NIBM Model Portfolio & Updates - pgs. 28-32

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This month's Main Story is on Contract Research Organizations (CROs). These "pick-and-shovel" firms help drug and biotechnology companies take their drugs through clinical trials. We review and evaluate fourteen companies according to our stated investment thesis.

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The following is an outline of this issue of the NIBM Newsletter.

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Main Story
Summary
Introduction
Investment Thesis
Disclosure
General concept
Warnings
What makes CROs tick?
Potential market size
Table: Worldwide R&D spending
Table: Worldwide outsourced R&D
CenterWatch report
Table: CenterWatch top seven CROs
Our Survey - The Next Phase™ Consultancy
Industry Trends
Mergers and Acquisitions
Focus on biotechs
Shift to risk-based agreements
CROs as biotech companies
CROs as venture capital companies
Industry consolidation and strategic acquisitions
FDA approval delays
Evaluating CROs
EPS
Gross Margin
Backlog
Top 5 concentration
Days sales outstanding
Market Cap
Contract Research Organizations
Table: CRO Company Breakdown
Quintiles (QTRN)
Sidebar: What do we mean by 'Earnings Quality'?
Covance (CVD)
Ingenix, a UnitedHealth Group subsidiary (UNH)
Table: UNH vs. Ingenix revenues
PPD, Inc. (PPDI)
PAREXEL (PRXL)
Kendle (KNDL)
MDS, Inc. (MDZ)
Omnicare
Table: Omnicare/CRO revenue comparison
ICON, Plc. (ICLR)
Table: Indications as percent of revenue
aaiPharma (AAII)
BioReliance (BREL)
The Covalent Group (CVGR)
Celeris (NASDAQ-OTC:CRSC)
US Oncology (USON)
Table: Summary of opinion
What Can Go Wrong
Macro Market Commentary
News Briefs
Herceptin gets mixed results in single-agent trial
Inspire Pharmaceuticals (ISPH) announces bad news on INS365
Imclone (IMCL) botches Erbitux filing, entire sector suffers
Univ. of Washington research finds link between AAV and genetic changes
NIBM Model Portfolio and Updates
Dendreon (2 pages)
Nabi
Targeted Genetics
Genta
NIBM Model Portfolio Addition
 
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