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 October 2002 (v02-n10) - Anniversary Issue
See the complete outline below.
 
This is a special issue of our newsletter. We provide detailed updates on all the companies currently in our Model Portfolio. Weighing in at 59 pages, this is by far the largest issue we have ever done. The content goes beyond updates, however. We spoke with all but two management teams for the purpose of this issue and we learned some fascinating things.

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If you are interested in one of the companies listed below you cannot miss this issue.

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In addition to updated milestone tables for all companies, we asked each management team the following five questions:
  1. You are in a room with your peers from the other companies in our Model Portfolio. The audience will invest in only one company. Give me two or three reasons why it should be your company.
  2. What is the most important strategic decision you’ve made in the last year?
  3. What needs to happen in the industry or in the market to increase biotechnology company valuations?
  4. What are you doing between now and the end of the year to increase your company’s market cap?
  5. Does any member of the executive team currently have a hedge, collar, or similar position on your company's stock or stock options?

Find out what your CEO will be doing to increase shareholder value this year (Question 4).

Discover which top two executives of one of the companies listed below made nearly $10 million hedging their own company's stock -- and didn't disclose it in their 10-K or 10-Q filings (Question 5).

Learn what eleven top biotech executives think is wrong with their industry and how to fix it (Question 3).

The following is an outline of this issue of the NIBM Newsletter. To read the introduction to this issue, click here.

Subscriber direct access

 
Introduction
About the format
Order matters
The 'Five Questions'
1 - ID Biomedical (IDBE)
Disclosure
 
A winner
Table: ID Biomedical Timelines
 
THE nasal flu vaccine
Challenge study
      Table: FluMist AV003 challenge study results
Partnership
FluINsure timelines
 
Table: ID Biomedical Biotech Monthly Publication History
May 2002 Main Story (15 pages)
Seven updates
 
Other Products
StreptAvax
Mystery vaccine
Allergy vaccine

Investment Case

Five Questions

2 - Dendreon (DNDN) pp. 8-12
 
Disclosure
 
Standing amongst the wreckage
Table: Dendreon Timelines
 
Provenge reborn
Partner
PROTECT (P-11)
Provenge focused
 
Table: Dendreon Biotech Monthly Publication History
November 2001 Main Story (25 pages)
Thirty-three updates
 
Mylovenge

APC 8024

Monoclonal antibodies

Investment Case

Five Questions

3 - Indevus (IDEV) pp.13-17
 
Disclosure
 
Unrecognized value
Table: Indevus Timelines
 
Trospium
Trial results
Manufacturing cloud
Partner
Timing
 
Pagoclone
Where from here?

CT-3

Citocoline

Dersalazine
 
Table: Indevus Biotech Monthly Publication History
February 2002 Main Story (12 pages)
Nine updates

Investment Case

Five Questions

4 - Genta (GNTA) pp. 18-23
 
Disclosure
 
Duck! It's a battleground!
Table: Genta Timelines
 
Genasense
Current pivotal trials
The Big Five
 
Ganite
Where from here?
 
Table: Genta Biotech Monthly Publication History
March 2002 Main Story (15 pages)
Thirty-three updates

Beyond Genasense

Organization

Upcoming Events
Table: Selected ASH 2002 Abstracts & Posters
 
Investment Case

Five Questions

5 - Alteon (AMEX:ALT) pp. 24-27
 
Disclosure
 
Restoring old hearts
Table: Alteon Timelines
 
ALT-711
Trial changes
 
ALT-744
 
ALT-946
 
Partnership
When
How Much
 
Table: Alteon Biotech Monthly Publication History
July 2002 Main Story (16 pages)
Five updates
 
Investment Case

Five Questions

6 - Seattle Genetics (SGEN) pp. 28-31
 
Disclosure
 
Young, smart, focused
Table: Seattle Genetics Timelines
 
Product Updates
SGN-14
SGN-30
SGN-15
SGN-25 and SGN-35
 
Table: Seattle Genetics Biotech Monthly Publication History
June 2002 Main Story (14 pages)
Three updates
 
Investment Case

Five Questions

7 - Esperion (ESPR) pp. 32-35
 
Disclosure
 
Huge market, experienced team
Table: Esperion Timelines
 
Products for fatty people
ETC-588 (LUV)
ETC-642 (RLT peptide)
ETC-216 (AIM)
ESP-31015 (Oral small molecule)
ETC-276
 
Table: Esperion Biotech Monthly Publication History
April 2002 Main Story (16 pages)
Seven updates
 
Partnerships
 
Investment Case

Five Questions

8 - PAREXEL (PRXL) pp. 36-39
 
Disclosure
 
Profitable picks and shovels
 
About PAREXEL
Concentration
Margins
Development programs
 
Table: PAREXEL Biotech Monthly Publication History
January 2002 Main Story (23 page industry review)
Nine updates
 
Investment Case

Five Questions

9 - Discovery Labs (DSCO) pp. 40-42
 
Disclosure
 
Coating your lungs is a good thing
Table: Discovery Labs
About the last issue
50,000 foot level
 
Table: Discovery Labs Biotech Monthly Publication History
September 2002 Main Story (9 pages)
 
CollaGenex deal
 
Investment Case

Five Questions

10 - Targeted Genetics (TGEN)
 
Disclosure
 
Plugging away at gene therapy
Table: Targeted Genetics Timelines
 
Cystic Fibrosis
 
Other products
E1A program
AIDS vaccine, hemophilia, and rheumatoid arthritis
 
Elan
 
CellExSys
 
Table: Targeted Genetics Biotech Monthly Publication History
December 2001 Main Story (24 pages)
Seventeen updates
 
Investment Case

Five Questions

11 - AltaRex (TSE:AXO) pp. 46-48
 
Disclosure
 
Sad story
Table: AltaRex Timelines
 
OvaRex at United
 
Other products
Table: AltaRex product pipeline
 
What's left for AltaRex?
 
Table: AltaRex Biotech Monthly Publication History
February 2002 Main Story (7 pages)
Ten updates
 
Investment Case

Five Questions

12 - Nabi (NABI) pp. 49-51
 
Disclosure
 
Are we there yet?
Table: Nabi Timelines
 
StaphVAX
 
NicVAX
 
Civacir
 
Table: Nabi Biotech Monthly Publication History
Debut Issue 2001 Introduction
Thirteen updates
 
Investment Case

Five Questions

13 - Titan Pharmaceuticals (AMEX:TTP) pp. 52
 
Disclosure
 
An interesting story
 
Shocking disclosure
 
Fallout
 
Product review
Iloperidone
Spheramine
Pivanex
CeaVac
 
Table: Titan Pharmaceuticals Biotech Monthly Publication History
Debut Issue 2001 Main Story (23 pages)
Seventeen updates
 
Investment Case

Five Questions

Macro Market Commentary
Finally, an incoming tide
 
NIBM Model Portfolio Performance
 
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