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 February 2004 (v04-n02)
Main Story - pgs. 1-11 Forbes Medi-Tech (FMTI)
Macro Market Commentary - pgs. 12-14
Biotech Monthly Coverage Update - pg. 15-24
NIBM Model Portfolio - pg. 25
(Full outline below...)

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Forbes Medi-Tech (“FMTI” from here forward) is a Canadian company focused on the most lucrative class of prescription drugs in the world – drugs for the treatment of hyperlipidemia or high cholesterol.

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The company’s lead product is FM-VP4, an engineered version of a phytosterol in a pill form. Phase I trial data shows no side effects. Preclinical data shows the drug’s mechanism of action is to block absorption of cholesterol from foods and block absorption/prevent re-processing of cholesterol from the liver. FM-VP4 is in early Phase II trials now.

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The following is an outline of this issue of the NIBM Newsletter.
Main Story - Forbes Medi-Tech (FMTI)
Introduction
Table: Basic Facts
Disclosures
Investment Case
Cholesterol absorption
Winds of change
Zetia (ezetimibe)
Mechanism of action
Clinical effect
Side effects
Phytosterols
Mechanism of action
Clinical effect
Side effects
FMTI products
Manufacturing process
FM-VP4
Mechanism of action
Clinical trials
Side effects
Competition
Market potential
Partnering
Reducol
Other pipeline
 
Miscellaneous
Table: Forbes Medi-Tech selected milestones
 
What Can Go Wrong
Macro Market Commentary - "Four months too soon"
Table: FDA top Spot history and the NASDAQ Biotech Index

Biotech Monthly Coverage Updates

Genta (four pages_
Updated survival information
Do it anyway
Why doesn't the FDA want the update?
So when do we see the data?
Investment Case
Nabi
Dendreon
Partnership
Targeted Genetics
tgAAVCF data
Offering
CellExSys
Indevus
ID Biomedical
Seattle Genetics
Discovery Labs (4 pages)
RDS Prevention Trial
Treating preemies
Early administration of surfactant
Importance of aerosolized Surfaxin trials
Pilot 2 program
The Low Stock Price
Alteon
Aphton

NIBM Model Portfolio Performance

 
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