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 April 2004 (v04-n04)
Main Story - pgs. 1-9 Dendritic cell therapies - Part 2
Macro Market Commentary - pgs. 10-11
Biotech Monthly Coverage Update - pg. 12-22
NIBM Model Portfolio - pg. 23
(Full outline below...)

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Last month we addressed the basic science behind dendritic cell therapies. This issue we outline three companies we believe solidify the scientific information we presented last month.

In the coverage update section, we also provide analysis of how the panel for the Genta ODAC meeting is likely to vote on three questions we feel likely to come up at the meeting.

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Our scope in this Main Story is to focus on the basic science behind dendritic cell therapies and illustrate what the investor is likely to encounter while doing due diligence on their investments.

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The following is an outline of this issue of the NIBM Newsletter.
Main Story - Dendritic cell vaccines -- Part 2
Introduction
Disclosures
Investment Case
Table: Dendritic cell vaccine companies
Dendreon
Science
Single antigen
Antigen cassette
Manufacturing
Products
Provenge
APC-8024 (Neuvenge)
Pipeline
Table: Dendreon's dendritic cell therapy pipeline
Merix Bioscience
Science/Manufacturing
Products
HIV/AIDS
Cancer
Infectious disease
 
Cell Genesys
Science
Products
GVAX non-patient specific
GVAX Bystander
GVAX patient-specific
Wrapping it up
 
Macro Market Commentary - "Which Bubble is your Bubble"

Biotech Monthly Coverage Updates

Genta (7 pages: ODAC vote forecast)
Iressa experience
Table: Votes by panel members common to Iressa & Genasense
Lessons for Genasense
Bexxar meeting
Table: Votes by panel members common to Iressa & Genasense
Lessons for Genta
December 2003 ODAC endpoints panel
Likely panel questions from the FDA
Table: Genasense panel voting predictions
Investment Case
Risk/reward - do this at home!
Table: Genta weighting portfolio risk analysis
Targeted Genetics
Indevus
ID Biomedical
Discovery Labs
Alteon
ZymoGenetics
Introgen
Medarex
SciClone
Investment Case

NIBM Model Portfolio Performance

 
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