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 October 2004 (v04-n10)
Main Story - pgs. 1-12 BioMarin Pharmaceuticals
Macro Market Commentary - pgs. 13-18
Research Director Commentary - pgs. 19-22
Biotech Monthly Coverage Update - pg. 23-31
NIBM Model Portfolio - pg. 32
(Full outline below...)

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BioMarin (BMRN) is an interesting company focusing on orphan diseases for the pediatric market. They recently acquired another company, picking up a marketed drug and a pediatric sales force. Management turnover and nearly resolved problems in the acquisition have pushed BioMarin's stock price lower.

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With news in the near-term, a market cap barely above cash, and a new management team, BioMarin is deserving of exploration.

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The following is an outline of this issue of the NIBM Newsletter.
Main Story - BioMarin Pharmaceuticals (BMRN)
Introduction
Table: Basic facts on BioMarin
Disclosures
Investment Case
Acquisition of Ascent Pediatrics
Table: Payment schedule
 
Target Indications
MPS (Mucopolysaccharidosis)
PKU (phenylketonuria)
Table: Targeted Pediatric Diseases
 
Clinical Development
Table: Product pipeline
Table: Product development tactics
Aldurazyme
Orapred
Aryplase
Phenoptin
Phenylase
Vibrilase

What Can Go Wrong

Table: BioMarin selected Milestones

Macro Market Commentary - "Another pivot point for biotech"
 
Research Commentary - "Random Thoughts from our Research Director"

Biotech Monthly Coverage Updates

Dendreon (we note this was written prior to the news on 10/28)
9901 data
Partnership agreement
Completion of 9902b enrollment
Taxotere
Used mosaic info
Bear case
Investment Case
Alteon
Aphton
Corcept
Discovery Labs
Genta
ID Biomedical
Table: Fluviral benefit matrix
Indevus
Aminocandin
Investment Case
Introgen
Nabi
Onyx
Investment Case
Pharmos
Sonus
Targeted Genetics
Valentis
ZymoGenetics

NIBM Model Portfolio Performance

 
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