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 May 2006 (v06-n05)
Main Story - Inside Clinical Trials - pgs. 1-15
Macro Market Commentary - pgs. 16-18
Research Director's Rant - pgs. 19-21
BSR Coverage Update - pgs. 22-34
Biotech Sector Short Interest - pg. 35
BSR Model Portfolio - pgs. 36-37
(Full outline below...)

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May's Biotech Monthly takes a peek inside the business of clinical trials. We examine how money and the search for academic fame and power affect investors in development-stage biotechnology companies. Working with real examples, we project how companies can game the clinical trial system to keep a leg up on their competitors.

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The following is an outline of this issue of Biotech Monthly.
Main Story - Inside Clinical Trials
Introduction

Investment Case

Data
Academic centers vs. community clinics
Patient baseline health
Patient motivation
Quality of data generated
Foreign influx
Fame & Power
The pharmaceutical-university complex
The central problem
Examples: Large study paralysis
Unusual business as usual
University/academic center involvement
Money
Clinical trial budget example
How sites are paid
How to game the system
One big conspiracy?
Investor impact
When is a delay, a delay?
"Stupid" changes in protocol
Thought leader advice to Wall Street
Advisory panel impacts

Bottom line

Macro Market Commentary - "So, what do you think?"

Research Director Rant - "Amish and the tempting of biotechs"

Biotech Monthly Coverage Updates

Adolor
Table: Company statistics
Investment case
Dendreon
Amgen's denosumab
Preclinical data
Investment case
Discovery Labs
Investment case
Forbes Medi-Tech
Table: Company statistics
Investment case
Genta
Hana Biosciences
Indevus
Introgen
Medarex
Investment case
Nabi
Investment case
Praecis
Repros Therapeutics
Table: Repros milestones
Investment case
SciClone
Sonus Pharma
Targeted Genetics
ZymoGenetics

Biotech Sector Short Interest

BSR Model Portfolio Performance

 
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